Left Ventricular global longitudinal strain predicts heart failure readmission in acute decompensated heart failure
نویسندگان
چکیده
BACKGROUND The goal of this study was to determine if left ventricular (LV) global longitudinal strain (GLS) predicts heart failure (HF) readmission in patients with acute decompensated heart failure. METHODS AND RESULTS Two hundred ninety one patients were enrolled at the time of admission for acute decompensated heart failure between January 2011 and September 2013. Left ventricle global longitudinal strain (LV GLS) by velocity vector imaging averaged from 2, 3 and 4-chamber views could be assessed in 204 out of 291 (70%) patients. Mean age was 63.8 ± 15.2 years, 42% of the patients were males and 78% were African American or Hispanic. Patients were followed until the first HF hospital readmission up to 44 months. Patients were grouped into quartiles on the basis of LV GLS. Kaplan-Meier curves showed significantly higher readmission rates in patients with worse LV GLS (log-rank p < 0.001). After adjusting for age, sex, history of ischemic heart disease, dementia, New York Heart Association class, LV ejection fraction, use of angiotensin converting enzyme inhibitors or angiotensin receptor blockers, systolic and diastolic blood pressure on admission and sodium level on admission, worse LV GLS was the strongest predictor of recurrent HF readmission (p < 0.001). The ejection fraction was predictive of readmission in univariate, but not in multivariate analysis. CONCLUSION LV GLS is an independent predictor of HF readmission after acute decompensated heart failure with a higher risk of readmission in case of progressive worsening of LV GLS, independent of the ejection fraction.
منابع مشابه
Prognosis of emergency room stabilization of decompensated congestive heart failure with high dose lasix
Objective: Congestive heart failure (CHF) has become one of the most important health care problems in western countries. This article focuses on the outpatient diagnosis and management of heart failure. We want to compare the outcome of patients who were treated with high dose diuretics in the emergency department (ED) without admission with patients who were admitted to hospi...
متن کاملBackground & Objective : Heart failure is a clinical syndrome and increases in rate by aging. Because changes in ECG and electrolytes are variable, specific and sometimes independent to the disease with different methods to be diagnosed, in this study we tried to find a way to diagnose them. Materials & Methods: This is a retrospective descriptive-analytic study. Data was collected from dec...
متن کاملبررسی فراوانی نشانگر CTnI و عوامل مرتبط با آن در بیماران با دیاستولیک دیسفانکشن AHF (PEF)
Abstract Background: Diastolic heart failure comprises 50 percent of cases of heart failure. The implications of increased levels of cardiac troponin I (CTnI) on congestive heart failure with preserved systolic function (AHF PEF) have been poorly evaluated. We hypothesized that its level might be elevated in AHF PEF so this evaluation was done in patients referred to Taleghani hospital with ...
متن کاملErratum: Serum bilirubin as a prognostic marker in patients with acute decompensated heart failure
BACKGROUND/AIMS Several prognostic markers for heart failure (HF) have been determined but the importance of liver function tests (LFTs) remains unknown. The aim of this study was to determine the prognostic significance, if any, of abnormal LFTs in acute decompensated HF. METHODS All adult patients (> 18 years of age) who were admitted to a community hospital with a diagnosis of acute decomp...
متن کاملAbnormal Global Longitudinal Strain Predicts Future Deterioration of Left Ventricular Function in Heart Failure Patients With a Recovered Left Ventricular Ejection Fraction.
BACKGROUND Patients with recovery of left ventricular ejection fraction (LVEF) remain at risk for future deterioration of LVEF. However, there are no tools to risk stratify these patients. We hypothesized that global longitudinal strain (GLS) could predict sustained recovery within this population. METHODS AND RESULTS We retrospectively identified 96 patients with a reduced LVEF <50% (screeni...
متن کامل